Creative BioMart, one of the world leaders in serving science, today announced the launch of a series of PROTAC targets and E3 ligases, research use only products that help accelerate drug discovery.
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Creative BioMart, one of the world leaders in serving science, today announced the launch of a series of PROTAC targets and E3 ligases, research use only products that help accelerate drug discovery.
When compared to conventional drug discovery methods, PROTACs have a number of advantages. The PROTAC just needs to selectively bind anyplace in the target to promote its destruction. This innovative approach offers the following benefits: many previously thought untargetable proteins (such as transcription factors) that are involved in the physiopathology of a disease have now been revealed to be potential PROTAC targets. Additionally, by deciding which E3 ligase the PROTAC will recruit, cell selectivity may be attained.
In the reported studies, researchers prefer to choose kinase as the target of protein degradation. According to incomplete statistics, about 54 kinases can be degraded by protein degrading agents based on PROTAC. At present, 518 kinases have been found.
To support PROTAC research and therapeutics, Creative BioMart now provides a comprehensive list of PROTAC targets and E3 ligases.
PROTAC Targets
TKL, CMGC, AGC, Atypical, CAMK, Non-RTK, RTK, STE, CK1, etc.
E3 ligases
BRD4, HSP70/HSPA1A, alpha-Synuclein, HECTD3, FBXW7, HUWE1, RNF126, C-Cbl, HSP10/EPF, HSP90 alpha, Tau, NEDD4, SKP2, WWP1, BCA2, CHIP, RBX1, APC/C, RNF138, TRIM25, etc.
According to Linna, the chief marketing staff at Creative BioMart, the company can also create proteins that suits specific experimental needs based on their years’ experience in protein production and purification.
Moreover, a wide range of PROTAC services are available at Creative BioMart, covering E3 ligase and target protein development service, Ligand discovery and design service, PROTAC in vitro evaluation, PROTAC in vivo evaluation, and Targeted protein degradation service.
For more information on the PROTAC targets and protein products related, please visit https://www.creativebiomart.net/product/protac-targets_4117.htm.
About Us: Starting from a small supplier of proteins and enzymes for academic institutes and biotech companies, Creative BioMart has always been focusing on developing high quality protein products and efficient protein manufacturing techniques. Over the past decade, our products and services are proved to have served our customers well and our brand has become one of the most trustworthy in the market.
Contact Info:
Name: Caroline
Email: Send Email
Organization: Creative BioMart
Website: https://www.creativebiomart.net/
Release ID: 89080998
